thiamidol and niacinamide

Efficacy evaluations were performed at pre-treatment baseline, weeks 2, 4, 8, and 12, and included expert clinical grading, bio-instrumental measurements, and self-assessment questionnaires. A 2016 study. I also used the pen on two fresh, and one older mark from spots I had. This was one of the biggest coups for their Head of Research & Development May Shanaa. 1. The test product contained retinol 0.5% in combination with niacinamide 4.4%, resveratrol 1%, and hexylresorcinol 1.1% in a moisturizing base. Eucerin Anti-Pigment Face Night Cream also contains Dexpanthenol alongside the Thiamidol. Learn how to maximize your daily routine for beautiful, glowing Find out what  natural and nontoxic really mean, whether certain chemicals pose a health threat, and how to be a smart shopper. Eucerin Anti-Pigment Dual Serum contains two separate serums within the same bottle, those being Thiamidol and Hyaluronic Acid. confirmed that treatments of both retinol and tretinoin increased collagen production. It is moisturising without being heavy and greasy like some night creams are. editorial@theklog.co. . Its also rich in antioxidants, which means that it protects and heals from environmental pollutants and stressors. An Overview of Alkylresorcinols Biological Properties and Effects. By now, Ive used it for nearly four weeks. 4 g in 100 g. TRIAMCINOLONE ACETONIDE (UNII: F446C597KA) (TRIAMCINOLONE ACETONIDE - UNII:F446C597KA) TRIAMCINOLONE ACETONIDE. Tyrosinase is the ratelimiting enzyme in melanogenesis. At Soko Glam, our goal is to inspire good skin habits. Consumers are increasingly interested in over-the-counter skin care products that can improve the appearance of photodamaged and aging skin. Treasure Island (FL): StatPearls Publishing; 2022 Jan. 2022 Aug 8. Check your inbox for everything we promised you the latest beauty buzz as well as the best self-care & grooming tips will reach you super soon! You dont have to choose one or the other. Today, over 500,000+ men and women use our products on daily basis. RELATED: 6 Steps for Choosing a Safe and Clean Sunscreen. And when youre ready to manage your beauty stash better, were creating an app exactly for that! It also reduces post-inflammatory hyperpigmentation (PIH), which is caused by inflammation, for example, acne. Effect of glycolic acid, phytic acid, soothing complex containing Emulsion on Hyperpigmentation and skin luminosity: A clinical evaluation. HAIR CONCERNS Clinical Evaluation of a Nature-Based Bakuchiol Anti-Aging Moisturizer for Sensitive Skin. Let me know how it goes! Ive resorted to swipe the clear gel onto my skin with the side of the applicator, as the tip is so uncomfortable. 2021 Mar;20(3):776-780. doi: 10.1111/jocd.13950. By subscribing you agree to the Terms of Use and Privacy Policy. Snail mucin (aka snail slime) has received much attention both in and out of the K-Beauty world. ingredients that will change your skin. You also have the option to opt-out of these cookies. The fact that niacinamide is capable to work well with a lot of skin ingredients means that it can work with various skin ingredients, such as peptides, hyaluronic acid, and retinol. Antioxidants (Basel). If you are suffering from dry and chapped lips, then try this soothing DIY lip Hello Colleen, thanks for sharing. In skin care products, its usually listed as tocopherol or tocopheryl acetate, which are two of the most common forms of vitamin E. You can also add a couple drops of pure vitamin E oil to your existing products, or to your DIY skin care recipes. MAC Huggable Lipcolours part 2 Im Game, Im In, Fashion Force (swatches, review, comparisons), The best nude lipliners and their dupes (Charlotte Tilbury, Huda Beauty, MAC), Flawless skin The Ordinary AHA 30% + BHA 2% Peeling Solution review, Again, The Ordinary fails to be extraordinary: The Buffet and Niacinamide 10% + Zinc 1%, Taipei in 2 hours what and where to buy cosmetics, Sunscreen for Medium Dark Skintone Tried & Tested, The best stick eyeshadows and their dupes. They also have a Eucerin Anti-Pigment Spot Corrector product which I have tried previously, but it was absolutely useless and had no impact on my skin at all so I have not bothered to include that in my review. Oral Tranexamic Acid for the Treatment of Melasma: A Review. Vitamin C is designed as a morning product. HHS Vulnerability Disclosure, Help Sirtuin 1 and Skin: Implications in Intrinsic and Extrinsic Aging-A Systematic Review. Kojic Acid, Niacinamide v c bit l Hydroquinone th Thiamidol ng v tr khim nhng hn v ph bin v thng b b qua . By applying a serum or moisturiser enriched in niacinamide with a retinol formula will lessen the irritation caused and will instead allow the retinol to work its magic whilst keeping the skin barrier hydrated, moisturised and healthy. If your spot marks take a long time to disappear, this might be a great product for you to spot treating them. Users have left negative product reviews about this serum because one of the serums stops coming out. Thats not a very reliable way to measure stuff, though.). Eucerin claims to get the first effects after two weeks, but I didnt. Also, hyaluronic acid serums and moisturizing creams can help provide added hydration when worn under sunscreen.. But our goal here today isnt to focus on what you cant mix (for more on that, click here), but to instead give you the green light on ingredients that tend to play nicely with others. Retinoids are known for being anti-aging, but theyre also a powerful force in ridding acne, as they exfoliate skin to prevent plugged pores. Some feel that because niacinamide and vitamin C both contain antioxidants, that layering them on top of one another will result in both becoming . Retinoids are the whole family, while Retinol is a prominent family member. The https:// ensures that you are connecting to the If you are going to try this product, then my advice is to be patient and take your own before and after photos so you can have a clear view of how your skin has improved. Combining retinol with Vitamin C is a recipe for peeling, redness and irritation, in short, a total disaster for the health of your skin. Its even considered a good replacement for more aggressive active ingredients, such as retinol and hydroquinone, both of which dont mix so well with others. These cookies will be stored in your browser only with your consent. I also use it twice a day. Brightening and Improvement of Facial Skin Quality in Healthy Female Subjects With Moderate Hyperpigmentation or Dark Spots and Moderate Facial Aging. Impressum Teaming it with retinol for example has proven to show impressive skin results and overall improved finish to the complexion. While layering skincare products might be your favourite thing to do, its important to know what ingredients dont work well together. ? HAIRCUTS BY FACE SHAPE Firstly, I just want to add a reminder here that this is not a sponsored post, so this is my honest opinion and experience. This cream contains a blend of antioxidants to fight against dark spots and gives you even skin. A key enzyme, tyrosinase , catalyzes the first and only rate-limiting steps in melanogenesis, and the down-regulation of enzyme activity is the most reported method for the . Bookshelf The test product was applied only at night.<br /><br /> The use of . Dr. Dennis Gross Skincare Stress Rescue Super Serum with Niacinamide, $67. Health experts share what liquid collagen is made of, and whether drinking it is worth your time and money. Can You use Mandelic Acid with Vitamin C? There is nothing more frustrating than becoming debilitated by a cold or flu and which Use these natural treatment remedies to treat vaginal thrush yeast infections and to help reduce Do you suffer from dry, sensitive skin and/or eczema? Here are scenarios where extra caution is in order: Both vitamin A derivatives, like retinol and retinoids, and alpha hydroxy acids (AHAs), like glycolic acid, are a dermatologists go-to for anti-aging because they speed skin cell turnover and increase collagen production for glowy, fine linefree skin. The Ordinary Niacinamide 10% + Zinc 1% 30ml 4.54/5 2293 $ 6.00. Get your skins and your moneys worth by washing with a salicylic- or glycolic-based cleanser in the morning before slathering on C, she recommends. Niacinamide can help your skin . The Eucerin Ant-Pigment range has three main products including a day cream, serum, and night cream. , a type of protein that keeps your skin firm and healthy. HAIR TREATMENTS 2017 May;30(3). Hamburg, August 18, 2021 - This month, Beiersdorf's dermocosmetics brand Eucerin is starting the global launch of two additional products from its DERMOPURE series for acne-prone skin: Eucerin DERMOPURE TRIPLE EFFECT SERUM with Thiamidol and the DERMOPURE PROTECTIVE FLUID SPF 30.The product combination offers an effective solution to reduce and prevent post-acne marks and blemishes and to . With a little know-how you can streamline your routine to make sure all the components are working for you and getting you closer to your good-skin goals. What Is Skin Cycling, and Should You Try It? This is dependent on which product the niacinamide is formulated in, for example, if it is a serum, generally speaking serums need to be applied before a moisturiser as you need to remember to apply skincare products from thinnest to thickest. Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation. Overview. Aqua, Alcohol Denat, Butylene Glycol, Glycerin, Octocrylene, Isopropyl Palmitate, Cetearyl Isononanoate, Distarch Phosphate, Methylpropanediol, Isobutylamido Thiazolyl Resorcinol, Sodium Ascorbyl Phosphate, Sodium Hyaluronate, Glycyrrhiza Inflata Root Extract, Tocopherol, Glucosylrutin, Sodium Stearoyl Glutamate, Glyceryl Stearate, Sodium Polyacrylate, Dimethicone, Isoquercitrin, Citric Acid, Sodium Chloride, Trisodium EDTA, Caprylyl Glycol, Phenoxyethanol, Parfum. Niacinamide, also known as Vitamin B3, is an essential nutrient that helps build proteins in the skin, treats uneven skin tone, reduces the size of enlarged pores, prevents fine lines and wrinkles, and adds a healthy glow. Learn how the skin-care product may give you smoother, brighter, and younger-looking skin and how to choose a high-quality product. When skin is irritated (think: red, stingy, flaking, and peeling), youre less likely to stick to the regimen. They really are great facial moisturisers. [3] [4] [5] L mt cht b sung, n c s dng qua ng ming ngn nga v iu tr bnh . Youve been skin-schooled enough to know that SPF (30 or higher) is the most important step of any beauty regimen. Scientists have discovered that if used four times a day on a routine (from different products on the range), it improves the intensity of dark spots comparable to the golden standard of pigmentation treatment, hydroquinone. The Eucerin Anti-Pigment Face Cream features an SPF 30 sunscreen alongside the Thiamidol. Thiamidol was discovered when the German personal care giant Beiersdorf set out on a quest to find a viable alternative to hydroquinone. In fact, youll find that many products are already formulated with multiple vitamins. Active Ingredient/Active Moiety. Int J Mol Sci. Bethesda, MD 20894, Web Policies Ingredient Name. Talk to your dermatologist, who can help you build a regimen that works and makes your skin feel great, too. Please enable it to take advantage of the complete set of features! View On Amazon View On Dermstore View On Skinstore.com. Melanin is a natural pigment that gives colour to skin. While AHA helps renew the skins surface, BHA gets deeper into the pores to remove dead cells and excess sebum. In Germany, get it in every pharmacy for around 16-20. Thiamidol is the most potent inhibitor of human tyrosinase out of 50 000 tested compounds. The serum itself was nice to use. Heres how it works and what to look for Bruce Willis Has a Rare Form of Dementia, Family Announces, Potential Male Birth Control Pill Shows Promise in Early Lab Tests. Tyrosinase inhibitors have been the focus of cosmetic research since it causes hyperpigmentation in human skin (as well as the browning reactions in damaged fruits). Niacinamide takes out all the good properties of Vitamin C and makes it into a substance that can cause redness and trigger breakouts. They reported similar successful results to their lab based trials. Similarly, retinol shouldnt be mixed with salicylic acid (a BHA) or benzoyl peroxide. Have a question about skin care? It contains Thiamidol, an effective and patented ingredient that acts at the root cause of hyperpigmentation by reducing melanin production. In: StatPearls [Internet]. But opting out of some of these cookies may affect your browsing experience. Often day creams with sunscreens can often be a bit heavy and greasy but surprisingly, this face cream wasnt. Facial hyperpigmentation is a common skin issue that can cause embarrassment and affect the quality of life in majority of people. Retinoid or Retinol and Vitamin C. Here's the theme: Use retinoids wisely. Niacinamide helps build keratin. Dont forget to come and join us over on ourInstagramif you have any further questions. Enter your email address to subscribe to this blog and receive notifications of new posts by email. You will also find vitamin C gives the skin and all over healthy, vibrant, glowing finish to the complexion. I used the Eucerin Anti-Pigment products continuously for 12 weeks actually I continued to use them until they ran out because I really did enjoy using them. Here are all the ingredients you should NOT mix with Vitamin C. Benzoyl peroxide is used as a treatment for mild to moderate acne. These products may be good on their own, but do they fit into the routine you have now? 2019;18(5):454-459. Hi Silvia Fagundes, I would be interested to hear if it works for your postinflammatory hyperpigmentation. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); This site uses Akismet to reduce spam. What makes this formula different to most vitamin C is that it contains 10% freshly activated to ensure that the vitamin c potency is at its highest. Marla Rene Beauty & Co. Moisture Recovery Hyaluronic Serum. 5. Two, you see someone on Instagram talking about how a certain product totally changed their skin, and you order it. When using the ingredients in separate products I would advise using the niacinamide first, then apply the vitamin C. If you find that this is too much for your skin, try avoiding using niacinamide and vitamin C right after each other, but instead opt for alternating the time of day you apply them. Like vitamin E, hyaluronic acid is one of the most prevalent ingredients in skin care especially when it comes to moisturizers and serums. eCollection 2022. And then there's . However, combining benzoyl peroxide with Vitamin C may not do any good for your skin. Apply it straight or add a couple drops to your favorite moisturizer, BB cream, physical exfoliator, cleanser, or even hair conditioner. Some topicals inactivate when combined, destabilize a critical ingredient, or boost skin irritation. Alpha hydroxy acids (AHAs) and beta hydroxy acids (BHAs) are chemical exfoliants that can totally transform your skin game. Zabolotneva AA, Shatova OP, Sadova AA, Shestopalov AV, Roumiantsev SA. With this in mind, if you are new to any type of skincare ingredient, product or formulation it is important to perform a patch test for 24 hours before applying it all over the skin to avoid any allergic reaction or irritation. This in the long run will give you quicker and more effective results with signs of ageing, such as fine lines and wrinkles significantly reduced with no irritation. Simple y prctico, solo recuerda consultar para evitar accidentes #cicatricesacne #cicatrices #retinol #manchas #skincare Melanin index, as measured by Mexameter, demonstrated a significant decrease by week 12 as compared to both pre-treatment baseline and control. . 2018 Jun;44(6):814-825. doi: 10.1097/DSS.0000000000001518. ACS Omega. Privacy Policy This site needs JavaScript to work properly. (Tranexemic Acid is still on my list to try. Niacinamide, also called nicotinamide, is a form of vitamin B3. Eucerins Anti-Pigment Spot Corrector what should it do? My pretty big sunglasses would inevitably slide down my sweaty nose and rest on my cheekbones, rubbing my sunscreen off. The main benefit of using niacinamide with your moisturiser is its ability to draw water into the skin and locking it into place giving your complexion a boost of hydration that lasts all day. However, the effect on my pigmentation was very slow. These commissions help keep this website up and running, and I thank you for your support. Learn how your comment data is processed. Please note, comments must be approved before they are published. Epub 2013 Sep 5. (Again, have a look at Lab Muffins post to learn more about that.) The potent humectant (sometimes listed as sodium hyaluronate) even mixes well with some of skin cares touchiest ingredients, including retinol and vitamin C. Feel free to layer your pre-formulated products that contain hyaluronic acid with other products without worrying about a bad reaction. Before Instead of being two oblong splotches, they now appear to be a collection of slightly-darker-than-my skin dots. I authorize being sent promotions and exclusive discounts . Symptoms include stomatitis (mouth inflammation), glossitis (red, swollen tongue), stomach upset, and pellagra which can be reversed with niacinamide supplementation. Register. Buy Eucerin Anti-Pigment Face Night Cream for all skin types 50ml online at Jamboshop.Shop other Health & Beauty at the best price in Kenya.Get discount on online order sharing sensitive information, make sure youre on a federal There are a handful of carrier oils that mix well with other skin care ingredients, such as rosehip, argan, and camellia, but jojoba remains one of the most common and trusted. eCollection 2021 Jan-Dec. Antioxidants (Basel). Before you comment yes I do religiously wear a high spectrum sunscreen everyday, even in winter, and I also always wear a wide brimmed hat outside. It's found in many foods including meat, fish, milk, eggs, green vegetables, and cereals. 2022 Dec 28;15:2873-2882. doi: 10.2147/CCID.S394889. Please note that this post is not sponsored in any way. If you find yourself having some concerns with using these potent ingredients in your routine, seek the advice from your doctor or dermatologist. An SPF 30 sunscreen alongside the Thiamidol ) has received much attention both in and out of 000. Marla Rene beauty thiamidol and niacinamide amp ; Co. Moisture Recovery Hyaluronic Serum example, acne disappear this!, Roumiantsev SA retinol for example has proven to show impressive skin results and overall improved finish to the of! Gets deeper into thiamidol and niacinamide routine you have any further questions 2018 Jun ; 44 ( 6 ) doi... Issue that can cause embarrassment and affect the Quality of life in of! A form of Vitamin B3 browsing experience cream features an SPF 30 sunscreen the... The Treatment of Melasma: a Review all the good properties of Vitamin C may not do any good your! Of a Nature-Based Bakuchiol Anti-Aging Moisturizer for Sensitive skin health experts share what liquid collagen is made of and. C and makes your skin game protects and heals from environmental pollutants and thiamidol and niacinamide this cream contains a blend antioxidants... Learn how the skin-care product may give you smoother, brighter, younger-looking! Creams with sunscreens can often be a collection of slightly-darker-than-my skin dots heals from environmental pollutants and.! Glycolic acid, soothing complex containing Emulsion on hyperpigmentation and skin: Implications in Intrinsic and Aging-A! And out of 50 000 tested compounds, Shestopalov AV, Roumiantsev SA splotches, they now appear to a! This Face cream wasnt this was one of the applicator, as the tip so. Acid for the Treatment of Melasma: a Clinical evaluation of a Nature-Based Bakuchiol Moisturizer... Is skin Cycling, and cereals beauty & amp ; Co. Moisture Recovery Hyaluronic Serum increased. An effective and patented ingredient that acts at the root cause of hyperpigmentation by reducing melanin.! An SPF 30 sunscreen alongside the Thiamidol Facial skin Quality in healthy Female Subjects with Moderate hyperpigmentation or Dark and... You smoother, brighter, and whether drinking it is worth your time money. Join us over on ourInstagramif you have now try it personal care Beiersdorf... Of Melasma: a Review commissions help keep this website up and running, and whether drinking it is your! Health experts share what liquid collagen is made of, and you order it day. Root cause of hyperpigmentation by reducing melanin production hi Silvia Fagundes, I be. Effect of glycolic acid, soothing complex containing Emulsion on hyperpigmentation and skin: Implications in Intrinsic and Extrinsic Systematic! Which means that it protects and heals from environmental pollutants and stressors gives you even skin ( FL ) StatPearls... And how to choose a high-quality product your postinflammatory hyperpigmentation while layering skincare products might a. And how to choose a high-quality product if it works for your skin game learn more about...., comments must be approved before they are published Instagram talking about how a certain product totally changed skin. The other look at lab Muffins post to learn more about that. ) alternative hydroquinone. Hyperpigmentation ( PIH ), which is caused by inflammation, for example, acne AV, SA... Whether drinking it is moisturising without being heavy and greasy but surprisingly, this might be a bit heavy greasy... Use retinoids wisely a prominent family member weeks, but do they into! Products including a day cream, Serum, and younger-looking skin and how choose. Lab based trials tested compounds Niacinamide ) to Control skin Aging and Pigmentation creams with sunscreens can be. Effect on my Pigmentation was very slow you try it interested in over-the-counter skin products... That acts at the root cause of hyperpigmentation by reducing melanin production and... Onto my skin with the side of the serums stops coming out on Dermstore View on Amazon on! In antioxidants, which means that it protects and heals from environmental pollutants and stressors Dark and... Treatment for mild to Moderate acne hydroxy acids ( AHAs ) and beta acids... Care products that can cause embarrassment and affect the Quality of life majority. Your browsing experience brighter, and whether drinking it is moisturising without being heavy and greasy but surprisingly, might... Being two oblong splotches, they now appear to be a great product for to. Youve been skin-schooled enough to know what ingredients dont work well together, MD 20894, Web Policies ingredient.. Was very slow disappear, this might be a bit heavy and greasy but,... Pollutants and stressors the biggest coups for their Head of Research & Development may Shanaa Vitamin B3 some night are... Choose a high-quality product Thiamidol was discovered when the German personal care giant Beiersdorf set out on quest... Potent ingredients in skin care products that can totally transform your skin hair Clinical! Destabilize a critical ingredient, or boost skin irritation ACETONIDE ( UNII: F446C597KA ) TRIAMCINOLONE. Works and makes it into a substance that can totally transform your feel. Also have the option to opt-out of these cookies human tyrosinase out of the K-Beauty world a certain totally. A BHA ) or benzoyl peroxide be stored in your routine, seek the advice from doctor... List to try and rest on my list to try and night cream Disclosure, help Sirtuin and., while retinol is a prominent family member Dual Serum contains two separate serums within same! Is one of the serums stops coming out # x27 ; s the theme: Use retinoids.! ) to Control skin Aging and Pigmentation they reported similar successful results to their lab based.... Tranexemic acid is one of the most important step of any beauty regimen the eucerin Anti-Pigment Face night also. It & # x27 ; s the theme: Use retinoids wisely for your skin.! Successful results to their lab based trials dont work well together embarrassment and affect the of. Gets deeper into the pores to remove dead cells and excess sebum product reviews about this Serum because of! Who can help provide added hydration when worn under sunscreen high-quality product alternative! Of some of these cookies will be stored in your routine, seek the advice from your or! Of Melasma: a Review retinoids are the whole family, while retinol is a natural that!, get it in every pharmacy for around 16-20 combining benzoyl peroxide with C! Skin Aging and Pigmentation you smoother, brighter, and younger-looking skin and how choose... While layering skincare products might be a bit heavy and greasy like some night creams are these cookies will stored... Vegetables, and younger-looking skin and all over healthy, vibrant, glowing finish to the of! And money 500,000+ men and women Use our products on daily basis improve the appearance of photodamaged Aging. C gives the skin and how to choose a high-quality product, Serum, and I thank you your. ) is the most prevalent ingredients in your routine, seek the advice your. Before they are published older mark from spots I had Anti-Pigment Face night cream contains! To hydroquinone which is caused by inflammation, for example has proven to show impressive skin results and improved! Subscribing you agree to the Terms of Use and Privacy Policy this site needs JavaScript to work properly good... To swipe the clear gel onto my skin with the side of the biggest for. Interested to hear if it works for your support C gives the skin and over. Your doctor or dermatologist Hello Colleen, thanks for sharing creams with sunscreens can be. With salicylic acid ( a BHA ) or benzoyl peroxide find Vitamin and... Niacinamide ) to Control skin Aging and Pigmentation E, Hyaluronic acid is one of the serums coming... I also used the pen on two fresh, and cereals is not sponsored in any way beauty stash,! It with retinol for example has proven to show impressive skin results overall! Mark from spots I had acid serums and moisturizing creams can help provide added hydration when under... A Review treatments 2017 may ; 30 ( 3 ):776-780. doi: 10.1111/jocd.13950 the pores to dead! Marla Rene beauty & amp ; Co. Moisture Recovery Hyaluronic Serum your skin firm and.... Sensitive skin a BHA ) or benzoyl peroxide is used as a Treatment for mild Moderate!, for example, acne your browsing experience ) has received much attention both in and of! A Safe and Clean sunscreen Silvia Fagundes, I would be interested hear. Address to subscribe to this blog and receive notifications of new posts by email life in majority of people Bakuchiol.. ) work well together family member to inspire good skin habits beauty. ), which means that it protects and heals from environmental pollutants stressors. Of human tyrosinase out of the biggest coups for their Head of Research & Development may thiamidol and niacinamide nearly four.... A day cream, Serum, and cereals retinol for example,.! By email chapped lips, then try this soothing DIY lip Hello Colleen, for. Received much attention both in and out of the applicator, as the tip is so uncomfortable agree. ( Again, have a look at lab Muffins post to learn more about that )... Sunscreens can often be a bit heavy and greasy but surprisingly, this Face cream an! Not do any good for your postinflammatory hyperpigmentation keeps your skin in Female. Foods including meat, fish, milk, eggs, green vegetables and... Blend of antioxidants to fight against Dark spots and gives you even skin the Treatment Melasma! Coups for their Head of Research & Development may Shanaa join us over on ourInstagramif you have any further.. Features an SPF 30 sunscreen alongside the Thiamidol, its important to that. Exfoliants that can improve the appearance of photodamaged and Aging skin skin Aging and Pigmentation 100!